What we do
We use state of the art experimental facilities to collect millions of x-ray diffraction patterns from thin sections of human brain tissue from Alzheimer’s cases; and next generation signal and image processing strategies, including AI and ML, to process, organize and interpret these data.
We spark innovation where it’s needed most. The Ghana Bioinnovation Initiative empowers local talent to co-create life-saving medical technologies for rural West Africa. Through hands-on workshops, cutting-edge research, and global collaboration, we transform bold ideas into real-world healthcare solutions.
Cultivating Biomedical Entrepreneurship and Innovation in Ghana
At the heart of the Ghana Bioinnovation Initiative is a commitment to community-driven problem solving. We bring together academic partners, healthcare professionals, and students to identify urgent needs in rural clinics—and respond with innovative, practical solutions. From prototyping to deployment, our work fosters sustainable healthcare advances that are born in Ghana, built for Ghana, and capable of inspiring systems change across the continent.
Discover how innovation is transforming healthcare delivery in Ghana.
Localization of Fibrillar Polymorphs in Human Brain Tissue
We explore the structural and molecular foundations of Alzheimer’s disease using a multidisciplinary approach. Our research focuses on characterizing pathological protein aggregates and analyzing their effects on neuronal tissue. Through advanced techniques such as small-angle X-ray microdiffraction and high-resolution microscopy, we investigate how misfolded proteins—particularly amyloid-β and tau—form and spread in human brain tissue.Working in collaboration with neuropathologists at Mass General Hospital, we aim to deepen our understanding of the mechanisms behind neurodegeneration, with the ultimate goal of identifying potential biomarkers and therapeutic targets for early intervention.
Research Paper/Protocol Example
